Production and characterization of pellets using Avicel CL611 as spheronization aid

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Production and characterization of pellets using Avicel CL611 as spheronization aid.

PURPOSE The study looked into the feasibility of producing pellet using Avicel CL611 as spheronization aid by the extrusion/spheronization technique. METHODS Pellets were formulated to contain either 20% or 40% Avicel CL611 and lactose monohydrate as the other sole ingredient. Water is used as liquid binder. Quality of pellets and extrudates were analyzed for size distribution, shape, surface...

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ژورنال

عنوان ژورنال: Drug Development and Industrial Pharmacy

سال: 2013

ISSN: 0363-9045,1520-5762

DOI: 10.3109/03639045.2013.767827